Perfused Organ Panel
Our unique microphysiologial system, Perfused Organ Panel (POP), provides a platform for researchers that accelerates the development of pharmaceutical, cosmetic, chemical, and precision medicine products. This technology can be used during the preclinical stages of product development to quickly predict the effects a certain drug or chemical will have on the human body. Our POP platform is comprised of PerfusionPal integral insert system, the SeedEZ scaffolds, Blood Substitute that mimics the functions of hemoglobin in cell culture perfusion, and a pump set to deliver physiological, interstitital flow rates. In a human, over 98% of tissue demands for oxygen are delivered to cells by hemoglobin contained in red blood cells. By way of the Blood Substitute and the pump our POP microphysiological system provides, for the first time, in vivo-like oxygen delivery to tissues cultured in vitro.
Perfused Organ Panel
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SeedEZ Scaffolds
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Blood Substitute
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Clinically Relevant
Provides accurate data that assists researchers in identifying new drug targets & biomarkers
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Advanced Testing
Allows researchers to zero-in on the most promising treatments in drug design and development
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Efficient and Humane
Improves characterization of human cells and diseases in vitro to bypass the use of animal models
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Adjustable Flow Rate
Users can program the flow rates to mimic those in the body in various organs and organ systems
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SeedEZSeedEZ is a cell culture scaffold that enables cells to grow in three dimensions (3D) as in living tissues. It supports all cell types and extracellular matrices (ECMs) allowing for cell-cell and cell-ECM signaling for physiologically relevant functions in vitro.
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Robust Models
Enables researchers to make co-cultures of two, three or more different cell types
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Assay Multiplexing
Mix-and-measure assays run in the scaffold provide time-course cell analyses
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Portable Cultures
Routine transfer of cultures from a plate to a dish for high-resolution imaging
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Reproducible Results
Defined cell distribution in x, y, and z, yields precise results across experiments
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Blood SubstituteOur proprietary Blood Substitute provides efficient delivery of atmospheric gases to the cells growing in our system. It enables superior oxygenation and pH maintenance by mimicking the functions of hemoglobin which results in increased cell viability and function in vitro.
Patent No. 9,701,938
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Superior Oxyenation
Ensures that cells throughout the system receive oxygen and other gases uniformly
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pH Stability
Improves delivery of carbon dioxide for stable and balanced pH environment
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Improved Function
Enhances cell respiratory and drug metabolism, and organ-specific functions
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Extended Studies
Increases cell longevity, eliminating time restriction on research
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