Lena Biosciences
  • Home
  • Company
    • About us
    • Partners >
      • New Partnerships
    • Careers
    • News >
      • Press Dr. Eckhard von Keutz
    • Events
  • Technology
    • Overview
    • Science >
      • Why 3D?
      • Our 3D models
      • Cell Types
      • Assays
    • Perfused Organ Panel
    • SeedEZ
    • Blood Substitute
    • GradientEZ
    • Publications
    • Featured publication
  • Shop
    • Services >
      • Liver toxicity service
      • Mitochondrial toxicity service
    • Products >
      • Perfused Organ Panel microphysiological system
      • SeedEZ 3D cell culture scaffold
      • GradientEZ 3D cell invasion assay
    • Distributors
  • Support
    • Instructions
    • Cell Types
    • 3D cell-based assays
    • Applications
    • FAQs
    • Contact us

​Publications


​WE APPRECIATE YOUR HARD WORK !
Email [email protected] with a reference to the publication which uses our products
Get $200 credit off your next order
PUBLISHED BY OUR CUSTOMERS​
Lang L, Loveless R, Dou J, Lam T, Chen A, Wang F, Sun L, Juarez J,  Qin ZS, Saba BF, Shay C and Teng Y. ATAD3A mediates activation of RAS-independent mitochondrial ERK1/2 signaling, favoring head and neck cancer development.
J Exp Clin Cancer Res 41, 43. 2022.
DOI: 10.1186/s13046-022-02274-9​
https://jeccr.biomedcentral.com/articles/10.1186/s13046-022-02274-9
Shay C. and Teng Y. Evaluating the Anticancer Activity of Natural Products Using a Novel 3D Culture Model. In: Guest P.C. (eds) Physical Exercise and Natural and Synthetic Products in Health and Disease.
Methods in Molecular Biology, vol 2343, 2022. Humana, New York, NY. 
DOI: 10.1007/978-1-0716-1558-4_9​​
https://link.springer.com/protocol/10.1007/978-1-0716-558-4_9
Lang L, Wang F, Ding Z, Zhao X, Loveless R, Xie J, Shay C, Qiu P, Ke Y, Saba NF, Teng Y. Blockade of glutamine-dependent cell survival augments antitumor efficacy of CPI-613 in head and neck cancer. 
J Exp Clin Cancer Res. 2021 Dec 14;40(1):393.
DOI: 10.1186/s13046-021-01888-9​​
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945659/
Lang L, Xiong Y, Prieto-Dominguez N, Loveless R, Jensen C, Shay C, Teng Y. FGF19/FGFR4 signaling axis confines and switches the role of melatonin in head and neck cancer metastasis.
J Exp Clin Cancer Res. 2021 Mar 10;40(1):93. 
DOI: 10.1186/s13046-021-01888-9​​
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945659/
Mamouni K, Kim J, Lokeshwar BL, Kallifatidis G. ARRB1 Regulates Metabolic Reprogramming to Promote Glycolysis in Stem Cell-Like Bladder Cancer Cells.
Cancers (Basel). 2021 Apr 10;13(8):1809.
DOI: 10.3390/cancers13081809​
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069028/
Teng Y, Cho WC. Editorial: Going the Distance: Enabling 3D Cell Culture Systems for Biomedical Research and Drug Treatment.
Front Mol Biosci. 2021 May 10;8:685095.
DOI: 10.3389/fmolb.2021.685095​​
https://www.frontiersin.org/articles/10.3389/fmolb.2021.685095/full
Gao L, Xu Z, Huang Z, Tang Y, Yang D, Huang J, He L, Liu M, Chen Z, Teng Y. CPI-613 rewires lipid metabolism to enhance pancreatic cancer apoptosis via the AMPK-ACC signaling.
​J Exp Clin Cancer Res. 2020 Apr 28;39(1):73.
DOI: 10.1186/s13046-020-01579-x​
https://jeccr.biomedcentral.com/articles/10.1186/s13046-020-01579-x
Lang L, Lam T, Chen A, Jensen C, Duncan L, Kong FC, Kurago ZB, Shay C, Teng Y. Circumventing AKT-Associated Radioresistance in Oral Cancer by Novel Nanoparticle-Encapsulated Capivasertib.
Cells. 2020 Feb 25;9(3):533.
DOI: 10.3390/cells9030533​
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140405/​
Vo-Hoang Y, Paiva S, He L, Estaran S, Teng Y. Design and Synthesis of Arf1-Targeting γ-Dipeptides as Potential Agents against Head and Neck Squamous Cell Carcinoma.
Cells. 2020 Jan 24;9(2):286. 
DOI: 10.3390/cells9020286​
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072570/
Shay C., Lang L., Teng Y. (2020) Visualizing and Evaluating Cancer Cell Growth and Invasion by a Novel 3D Culture System. In: Guest P. (eds) Clinical and Preclinical Models for Maximizing Healthspan.
​Methods in Molecular Biology, vol 2138. Humana, New York, NY. ​
​https://doi.org/10.1007/978-1-0716-0471-7_9​
Caleb J and Teng Y. Is It Time to Start Transitioning From 2D to 3D Cell Culture? 
​Front. Mol. Biosci. 2020, 6:33
DOI: 10.3389/fmolb.2020.00033
​www.frontiersin.org/articles/10.3389/fmolb.2020.00033/full
Miller PG, Chen CY, Wang YI, Gao E, Shuler ML. Multiorgan microfluidic platform with breathable lung chamber for inhalation or intravenous drug screening and development.
​Biotechnol Bioeng. 2020 Feb;117(2):486-497.
DOI: 10.1002/bit.27188
https://onlinelibrary.wiley.com/doi/abs/10.1002/bit.27188​
Lang L, Shay C, Zhao X, Xiong Y, Teng Y. Simultaneously inactivating Src and AKT by saracatinib/capivasertib co-delivery nanoparticles to improve the efficacy of anti-Src therapy in head and neck squamous cell carcinoma. 
​J Hematol Oncol. 2019, 12:132.

DOI:10.1186/s13045-019-0827-1
https://jhoonline.biomedcentral.com/articles/10.1186/s13045-019-0827-1​
J Hematol Oncol 2019
File Size: 5163 kb
File Type: pdf
Download File

Xiong Y, He L, Shay C, Lang L, Loveless J, Yu J, Chemmalakuzhy R, Jiang H, Liu M, Teng Y. Nck-associated Protein 1 Associates with HSP90 to Drive Metastasis in Human Non-Small-Cell Lung Cancer.
​J Exp Clin Cancer Res. 2019, 38(1):122.
​DOI: 10.1186/s13046-019-1124-0
​https://jeccr.biomedcentral.com/articles/10.1186/s13046-019-1124-0
J Exp Clin Cancer Res 2019
File Size: 6054 kb
File Type: pdf
Download File

Morrissey B, Blyth K, Carter P, Chelala C, Holen I, Jones L, Speirs V. SEARCHBreast Workshop Proceedings: 3D Modelling of Breast Cancer.
Altern Lab Anim. 2015 Dec;43(6):367-75.
DOI: 10.1177/026119291504300604
https://journals.sagepub.com/doi/abs/10.1177/026119291504300604
AUTHORED BY LENA BIOSCIENCES​ AND COLLABORATORS
Reyes DR, Esch MB, Ewart L, Nasiri R, Herland A, Sung K, Piergiovanni M, Lucchesi C, Shoemaker JT, Vukasinovic J, Nakae H, Hickman J, Pant K, Taylor A, Heinz N, Ashammakhi N. From animal testing to in vitro systems: advancing standardization in microphysiological systems.
Lab Chip. 2024 Feb 27;24(5):1076-1087.
DOI: 10.1039/d3lc00994g
https://pubmed.ncbi.nlm.nih.gov/38372151/​
Liu P, Roberts S, Shoemaker JT, Vukasinovic J, Tomlinson DC, Speirs V. Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues.
PLoS One. 2023.
DOI: 10.1371/journal.pone.0283044 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019722/​
Shoemaker J.T., Zhang W., Atlas A.I., Bryan R.A., Inman S.W., Vukasinovic J. A 3D Cell Culture Organ-on-a-Chip Platform With a Breathable Hemoglobin Analogue Augments and Extends Primary Human Hepatocyte Functions in vitro. 
​Frontiers in Molecular Biosciences. 2020.
DOI: 10.3389/fmolb.2020.568777     
​www.frontiersin.org/articles/10.3389/fmolb.2020.568777/full
C. M. Didier, A. Kundu, J. T. Shoemaker, J. Vukasinovic and S. Rajaraman. SeedEZTM Interdigitated Electrodes and Multifunctional Layered Biosensor Composites (MLBCs): A Paradigm Shift in the Development of In Vitro BioMicrosystems. J Microelectromech S. 2020
DOI: 10.1109/JMEMS.2020.3003452
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982987/
​In vitro hepatocyte function is enhanced in a perfused 3D culture platform. James T. Shoemaker, Wanrui Zhang, Dennis G. McDuffie, Alejandro Badilla, Emmanuel Thomas, Jelena Vukasinovic. ​
​
Life Science Exhibits’ Virtual Conference:  Immunology | Infectious Disease | COVID-19 2020.
LSE - Immunology, Infectious Disease, COVID-19 2020
File Size: 2096 kb
File Type: pdf
Download File

Shoemaker JT, Richardson KR, Arnst J, Marcus AI and Vukasinovic J. ​Characterization of patient-derived organoids cultured on a gas-rich, liquid-liquid interface. ​
​American Association for Cancer Research 2019. Proceedings: Abstracts 1-2748

DOI: 10.1158/1538-7445.AM2019-54
http://cancerres.aacrjournals.org/content/79/13_Supplement/54
AACR 2019
File Size: 1257 kb
File Type: pdf
Download File

J.T. Shoemaker, J. Vukasinovic, C. Xu, Z. Wen, and M.C. LaPlaca. Neuroimmune activation and off-target toxicity testing of cell therapies using a novel brain-on-a-chip system.
​Society for Neuroscience 2018.
SFN 2018 - A
File Size: 3608 kb
File Type: pdf
Download File

J. Vukasinovic, J.T. Shoemaker, and M.C. LaPlaca. A perfused three-dimensional culture model of human cortical tissue.
Society for Neuroscience 2018.
SFN 2018 - B
File Size: 3464 kb
File Type: pdf
Download File

Sophie Roberts, Danah Al’Qallaf, Sally A. Peyman, Darren Tomlinson, J.T. Shoemaker, Jelena Vukasinovic and Valerie Speirs. ​Progress towards the development of a fully humanised 3D cell culture model of HER2+ breast cancer.
Breast Cancer Res Treat (2018) 167: 309. 
​DOI: 10.1007/s10549-017-4585-x
​https://link.springer.com/article/10.1007%2Fs10549-017-4585-x
Shoemaker J.T. and Vukasinovic J. Cytochrome P450 enzyme activity is enhanced in hepatocytes grown using a perfused 3D cell culture drug screening system. 
American Association for Cancer Research 2017. Volume 77, Issue 13 Supplement, pp. 4080.
​DOI: 10.1158/1538-7445.AM2017-4080

http://cancerres.aacrjournals.org/content/77/13_Supplement/4080
AACR 2017
File Size: 154 kb
File Type: pdf
Download File

​Shoemaker J.T. and Vukasinovic J. A perfused 3D cell culture platform for preclinical drug screening.
New Frontiers in 3D Cell Culture-based Screening Technologies. October 13, 2016. Baltimore, MD, USA
New Frontiers in 3D Cell Culture 2016
File Size: 153 kb
File Type: pdf
Download File

​
​​Learn about 3D cell culture and Perfused Organ Panel technology
ATTEND OUR EDUCATIONAL WEBINARS
REQUEST A SAMPLE
Privacy policy
Copyright © 2024
  • Home
  • Company
    • About us
    • Partners >
      • New Partnerships
    • Careers
    • News >
      • Press Dr. Eckhard von Keutz
    • Events
  • Technology
    • Overview
    • Science >
      • Why 3D?
      • Our 3D models
      • Cell Types
      • Assays
    • Perfused Organ Panel
    • SeedEZ
    • Blood Substitute
    • GradientEZ
    • Publications
    • Featured publication
  • Shop
    • Services >
      • Liver toxicity service
      • Mitochondrial toxicity service
    • Products >
      • Perfused Organ Panel microphysiological system
      • SeedEZ 3D cell culture scaffold
      • GradientEZ 3D cell invasion assay
    • Distributors
  • Support
    • Instructions
    • Cell Types
    • 3D cell-based assays
    • Applications
    • FAQs
    • Contact us