Lena Biosciences offers in vitro services using SeedEZ and PerfusionPal products.
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Toxicity
Hepatotoxicity Short-term and long-term DILI Off-target toxicity of cell therapies Toxicity of activated immune cells is measured after co-culture with 3D human organ models, or after incubation of 3D organ models in activated immune cell medium Cytotoxicity Using a client's cells and standard assays (CellTiter-Glo or total LDH, kinetic LDH release etc.) Drug metabolism and ddi
CYP450 inhibition and induction assays efficacy IN ADVANCED TUMOR MODELS
Advanced tumor models include 3D co-cultures of multiple cell types and the extracellular matrix. The efficacy may be tested in perfused and/or unperfused 3D tumor models. For activated immune cell testing, activated (effector) cells are co-cultured with tumor models. TISSUE MODELS
We can generate advanced 3D tissue models using co-cultures of primary cells or cell lines based on your specifications, or using cells provided by you. |